A new translation of Pierre Bayle's first great work, which undermines the influence of "superstition" in political life and laid the groundwork for the separation of church and state.

BackgroundIn this article, we address questions regarding how people consider what they do or do not consent to and the reasons why. This article presents the findings of a citizen forum study conducted by the University of Geneva in partnership with the Geneva University Hospitals to explore the opinions and concerns of members of the public regarding predictive oncology, genetic sequencing, and cancer. MethodsThis paper presents the results of a citizen forum that included 73 participants. A research tool titled "the (...) mechanics of consent" was designed for this study. This tool is a table encouraging participants to reflect on social and research actors, types of data, and desired levels of control while sharing different types of data with different actors. Participants’ discussion that led to the completion of each table were audio-recorded, transcribed, and analyzed using thematic analysis.ResultsThe results are a compilation of responses from the mechanics of consent tool divided into two sections; the first presents quantitative results of collective responses regarding attitudes to consent to donate their data. The second section present qualitative findings emerged from the discussion amongst participants.DiscussionChoice and control of personal data is crucial for the public to be able to decide who and how to trust. Key information to be disclosed to potential research participants shall include information about potential risks and benefits; who will be accessing and using their data; as well as assurances that their choice will be respected. Furthermore, researchers ought to make sure they are trustworthy, by acting in a competent, reliable, and honest manner. Governance systems ought to be better equipped to address ethical issues raise by the growing presence of non-traditional research actors, consent of exchanges of data via digital devices and online activity such as social media and fairness of data trading. Finally, informed consent is one of the various elements that contribute to conducting ethical research. More needs to be done to strengthen governance and ensure adequate protection of research participants, particularly to address issues related to predictive health analytics. (shrink)

Advances in artificial intelligence, as well as its increased presence in everyday life, have brought the emergence of many new phenomena, including an intriguing appearance of what seems to be a variant of body dysmorphic disorder, coined “Snapchat dysmorphia”. Body dysmorphic disorder is a DSM-5 psychiatric disorder defined as a preoccupation with one or more perceived defects or flaws in physical appearance that are not observable or appear slight to others. Snapchat dysmorphia is fueled by automated selfie filters that reflect (...) unrealistic sociocultural standard. In this paper, we discuss how body dysmorphic disorder and related body image distortions could arise, using the conceptual resources provided by the active inference framework. We suggest that these disorders involve dysfunctional self-modelling which entails maladaptive internalization of sociocultural preferences during adolescent identity formation. Identity formation is hereby described as cycles of interpersonal active inference that arbitrate between identity exploration and commitment. We propose that impaired self-modelling is unable to reduce interpersonal uncertainty during identity exploration, which, over time, degenerates into uncontrollable epistemic habits that isolate the body image from corrective sensory evidence. In light of these insights, we subsequently explore some of the consequences of image-centered social media platforms on the identity formation process. We conclude that heightened interpersonal uncertainty in this novel context could precipitate the onset of body dysmorphic disorder and related body image distortions, particularly when selfie filters are involved. (shrink)

Prosocial compensation is a corporate social responsibility practice that involves donating money to a charitable cause on behalf of customers as a means to compensate them for their loss after a service failure. In order to determine the effectiveness of PC, we carried out three experiments while also comparing its effectiveness within private and public settings. Experiment 1 focused on the signaling effects of communicating the promise to offer PC to potential customers in the event of service failure. Results show (...) that, in both private and public settings, PC has positive effects on corporate image, credibility, and word-of-mouth intent. More significantly, PC improved one’s CSR image, whereas more tangible compensation, such as a gift voucher, did not. Experiments 2A and 2B focused on the effects of offering PC after a service failure on perceptions of justice. Results show that PC contributes to perceived distributive justice, procedural justice, and post-recovery satisfaction in both private and public settings. Our study showed that PC could be a relevant new CSR practice for organizations wanting to enhance theirs CSR image while contributing to fulfilling their ethical and philanthropic CSR responsibilities. We discuss the implications of our findings and offer several avenues for follow-up research on this initial study on PC. (shrink)

This paper is about two kinds of mental content and how they are related. We are going to call them representation and indication. We will begin with a rough characterization of each. The differences, and why they matter, will, hopefully, become clearer as the paper proceeds.

It has been commonplace in epistemology since its inception to idealize away from computational resource constraints, i.e., from the constraints of time and memory. One thought is that a kind of ideal rationality can be specified that ignores the constraints imposed by limited time and memory, and that actual cognitive performance can be seen as an interaction between the norms of ideal rationality and the practicalities of time and memory limitations. But a cornerstone of naturalistic epistemology is that normative assessment (...) is constrained by capacities: you cannot require someone to do something they cannot or, as it is usually put, ought implies can. This much we take to be uncontroversial. We argue that differences in architectures, goals and resources imply substantial differences in capacity, and that some of these differences are ineliminable. It follows that some differences in goals and architectural and computational resources matter at the normative level: they constrain what principles of normative epistemology can be used to describe and prescribe their behavior. As a result, we can expect there to be important epistemic differences between the way brains, individuals, and science work. (shrink)

The mammalian pineal gland contains two types of N‐acetyltransferases which act on aromatic amines. One type preferentially acetylates arylamines such as phenetidine and aniline, whereas the other preferentially acetylates arylalkylamines such as tryptamine and phenylethylamine. The two enzymes can be distinguished by (1) molecular size, (2) regulation, and (3) inactivation characteristics. Arylalkylamine N‐acetyltransferase is involved in the regulation of melatonin synthesis in the pineal gland. A specific function of pineal arylamine N‐acetyltransferase has not been established; it may function as a (...) nonspecific detoxification mechanism. (shrink)

Pierre Soulages : régulièrement j’élimine des toiles, inabouties ou qui ont “tourné mal ”, banales, sans rien qui m’excite et qui sont d’ailleurs des sortes d’aventures avortées… Alors qu’à un moment, il y avait quelque chose qui était apparu, qui me paraissait intéressant à pousser, à intensifier, et puis ça s’est détourné, ça s’est terminé par quelque chose de morne, pas vraiment inachevé parce que l’inachevé c’est par rapport à un modèle parfait ou… qui n’est pas du tout ce (...) que je poursuiv... (shrink)

C'est à emprunter un chemin d'écolier que nous invite ce livre. Un chemin qui part d'une rencontre, celle de la pensée de Heidegger, dans la khâgne de Jean Beaufret en 1946, où se joue l'intime d'une vocation philosophique. Un chemin jalonné d'anecdotes savoureuses, où l'on croise toutes les grandes figures de la pensée française de la seconde moitié du XXe siècle, de Gandillac à Boutang, de Foucault à Michel Henry, dialoguant avec Platon, Montaigne ou Bergson. Un chemin où l'âme d'un (...) vieux maître d'école se recueille pour mieux se livrer, et "conjuguer une fois encore la poussière et l'étoile."--Page 4 of cover. (shrink)

Entre les actions judiciaires intentées contre l’inertie des États ou des grandes entreprises, les mouvements sociaux qui revendiquent une transition plus équitable et les sommets climatiques internationaux où elle est sans cesse invoquée pour négocier des accords, la justice climatique s’est installée comme un sujet politique majeur. En complément des analyses juridiques, politiques, sociologiques et économiques, une réflexion éthique est indispensable pour en saisir toute la portée. -/- Comment justifier l’objectif de limiter le réchauffement planétaire à 2 ou 1,5 °C (...) d’ici la fin du siècle ? Selon quels principes distribuer les droits d’émission et l’effort de lutte contre le changement climatique à l’échelle mondiale ? Seuls les États ou bien aussi les individus ont-ils des responsabilités ? Pierre André et Axel Gosseries exposent les concepts, principes et arguments qui structurent aujourd’hui la question de la justice climatique. (shrink)